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Process Capabilities 
 

 

 
PROCESS CAPABILITIES - NUCLEOSIDES
 
  • Protection and deprotection of nucleoside compounds
  • Transformation of U to C via triazolation process
  • 5-O-Acylations
  • Selective 2-O alkylations
  • Fluorination
  • Azidation and catalytic reduction to amino derivative
  • Phosphitylation
   
  PROCESS CAPABILITIES - NON-NUCLEOSIDES
 
  • Side Chain Photochlorination (Ar- CH3 to Ar-CH2Cl)
  • Cyanation (NaCN, KCN, CuCN)
  • Halogenation (Aliphatic/Aromatic)
  • Reactions with Phosphorous Halides
  • Catalytic Hydrogenation 30 Bar; 1500c
  • Grignard reactions

  • Friedel-crafts reaction
  • Wittig- Horner reaction
  • Metal / Ammonia reduction
  • Boron Chemistry
    (Borates, Boronic Acids, Boron Mediated Asymmetric Synthesis)
  • Organometallic reactions
  • Fries Rearrangement
  • Oxidations using Metal Oxides, H2O2, Per Acids, Hypochlorite
  • Reductions Using Metal Hydrides, Nobel Metals, Ni, Na/ EtOH, Al Isopropoxide, Chemical Reductions
  • Aromatic Fluorination, Sulphonation
  • Carbohydrate Chemistry


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